Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2106978 | 0.83 | MMP2 (0.39) | PYGLKDM4ELMNATP53L3MBTL1 | |
| SCHEMBL2107450 | 0.72 | PYGL (0.44) | MEN1KMT2ARXFP1PYGLGUSB | |
| SCHEMBL14144202 | 0.72 | PYGL (0.51) | PYGL | |
| SCHEMBL13271409 | 0.72 | CCNC (0.44) | MEN1KMT2APYGLLMNACHEK1 | |
| SCHEMBL27637879 | 0.71 | CTSA (0.47) | MEN1KMT2ARXFP1PYGL | |
| SCHEMBL1608873 | 0.69 | IDO1 (0.53) | MEN1KMT2APYGLFLT3MMP2 | |
| SCHEMBL1608889 | 0.69 | GUSB (0.51) | MEN1KMT2APYGLGUSBFLT3 | |
| SCHEMBL4721594 | 0.69 | CHEK1 (0.44) | MEN1KMT2APYGLKDM4ELMNA | |
| SCHEMBL31030817 | 0.68 | ALOX15 (0.59) | MEN1KMT2AKDM4ELMNAALDH1A1 | |
| SCHEMBL1202654 | 0.68 | ALOX15 (0.59) | MEN1KMT2AKDM4ELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158622-B2 | Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase | PROSIDION LIMITED (GB) | 2012-04-17 | — | — | US | disclosed |