SCHEMBL21074172

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2141676	0.90	ALDH1A1 (0.51)	ALDH1A1MAPK1L3MBTL1MEN1KMT2A
	SCHEMBL3421550	0.89	ALDH1A1 (0.47)	ALDH1A1MAPK1L3MBTL1TDP1MEN1
	SCHEMBL18686234	0.88	SYK (0.52)	ALDH1A1MAPK1L3MBTL1TDP1MEN1
	SCHEMBL25215663	0.88	HTT (0.46)	ALDH1A1MAPK1L3MBTL1TDP1LTA4H
	SCHEMBL18686203	0.84	SYK (0.48)	L3MBTL1TDP1MEN1KMT2ASYK
	SCHEMBL12990128	0.83	ALDH1A1 (0.53)	ALDH1A1MAPK1L3MBTL1TDP1KMT2A
	SCHEMBL22481266	0.83	ALDH1A1 (0.53)	ALDH1A1MAPK1L3MBTL1TDP1KMT2A
	SCHEMBL557536	0.82	ALDH1A1 (0.46)	ALDH1A1MAPK1L3MBTL1LTA4HMEN1
	SCHEMBL18668821	0.82	CYP1A2 (0.49)	ALDH1A1MAPK1L3MBTL1TDP1MEN1
	SCHEMBL15561400	0.81	SYK (0.48)	L3MBTL1MEN1KMT2ASYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.