⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25689262 | 0.76 | ARG1 (0.34) | — | |
| SCHEMBL13701208 | 0.73 | — | — | |
| SCHEMBL18797998 | 0.73 | — | — | |
| SCHEMBL21076286 | 0.73 | — | — | |
| SCHEMBL22299487 | 0.71 | PRMT3 (0.42) | — | |
| SCHEMBL16256528 | 0.68 | DRD2 (0.36) | — | |
| SCHEMBL18469419 | 0.67 | — | — | |
| SCHEMBL23568905 | 0.67 | PIK3CD (0.43) | — | |
| SCHEMBL25480677 | 0.66 | ALDH1A1 (0.39) | — | |
| SCHEMBL25478261 | 0.66 | CA12 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10933139-B2 | Conjugated lipomers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-03-02 | — | — | US | disclosed |
| US-20190167795-A1 | CONJUGATED LIPOMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-06-06 | — | — | US | disclosed |