SCHEMBL2107755

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2108336	0.97	ALOX5 (0.43)	ALOX5NPSR1TSHRALDH1A1JAK2
	SCHEMBL2108834	0.86	ALDH1A1 (0.39)	ALOX5NPSR1TSHRALDH1A1HPGD
	SCHEMBL2620013	0.82	ALOX5 (0.48)	ALOX5ALDH1A1SLC6A2SLC6A3SLC6A4
	SCHEMBL17517033	0.81	BRD4 (0.41)	TSHRALDH1A1HPGDHSD17B10KDM4E
	SCHEMBL7726271	0.80	ALDH1A1 (0.43)	NPSR1TSHRALDH1A1JAK2JAK3
	SCHEMBL2107714	0.80	SLC6A3 (0.61)	SLC6A2SLC6A3SLC6A4DHODH
	SCHEMBL317670	0.80	TSHR (0.47)	ALOX5TSHRALDH1A1HPGDHSD17B10
	SCHEMBL7546067	0.77	SLC6A3 (0.51)	CHRM2CHRM4CHRM5CHRM1CHRM3
	SCHEMBL5662430	0.77	KDM4E (0.46)	NPSR1ALDH1A1HPGDHSD17B10KDM4E
	SCHEMBL16061721	0.77	SLC6A3 (0.64)	NPSR1TSHRALDH1A1HPGDCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.