Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24697452 | 0.79 | HRH3 (0.32) | HRH3 | |
| SCHEMBL24260750 | 0.78 | KDM2B (0.39) | HRH3 | |
| SCHEMBL14463189 | 0.75 | HTR2A (0.32) | — | |
| SCHEMBL10863656 | 0.71 | HRH3 (0.34) | HRH3 | |
| SCHEMBL24069496 | 0.69 | KDM4E (0.36) | — | |
| SCHEMBL15185049 | 0.69 | — | — | |
| SCHEMBL12774192 | 0.68 | HRH3 (0.37) | HRH3 | |
| SCHEMBL12945956 | 0.68 | OPRM1 (0.33) | — | |
| SCHEMBL13620647 | 0.68 | ALDH1A1 (0.38) | HRH3 | |
| SCHEMBL24401977 | 0.68 | VNN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041841-B1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2019-06-05 | — | — | EP | disclosed |