Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27423166 | 0.79 | CHRM1 (0.38) | RAB9ACHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL27400861 | 0.77 | CHRM2 (0.40) | RAB9ACHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL29588116 | 0.76 | ALDH1A1 (0.41) | HTR6L3MBTL3L3MBTL1MEN1KMT2A | |
| SCHEMBL205363 | 0.76 | L3MBTL3 (0.39) | CHRM2CHRM1CHRM4CHRM3HTR6 | |
| Hydrochloric Acid SCHEMBL3953750 | 0.74 | ALDH1A1 (0.44) | HTR6L3MBTL3L3MBTL1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4139677 | 0.74 | ALDH1A1 (0.44) | HTR6L3MBTL3L3MBTL1MEN1KMT2A | |
| SCHEMBL21548010 | 0.72 | CHRM2 (0.42) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL29316595 | 0.70 | HTR6 (0.49) | RAB9ACHRM2CHRM1CHRM3HTR6 | |
| SCHEMBL10888360 | 0.70 | HTR6 (0.50) | HTR6L3MBTL3L3MBTL1LMNACYP2D6 | |
| SCHEMBL10863631 | 0.70 | HTR6 (0.42) | HTR6LMNACYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041841-B1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2019-06-05 | — | — | EP | disclosed |