Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21078030 | 0.83 | — | — | |
| SCHEMBL3838774 | 0.77 | HRH3 (0.41) | HRH4HRH3NCF1ACHE | |
| SCHEMBL20979478 | 0.76 | HTR3A (0.33) | HRH4 | |
| SCHEMBL24506016 | 0.76 | KCNH2 (0.31) | HRH3 | |
| SCHEMBL21646523 | 0.69 | HRH3 (0.40) | CYP1A2CYP2D6HRH4HRH3NCF1 | |
| SCHEMBL11597169 | 0.67 | — | — | |
| SCHEMBL24611582 | 0.66 | ACHE (0.45) | HRH3ACHECARM1PRMT6 | |
| SCHEMBL23323206 | 0.64 | — | — | |
| SCHEMBL19993148 | 0.64 | QDPR (0.31) | — | |
| SCHEMBL3436965 | 0.63 | PRMT6 (0.62) | CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041841-B1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2019-06-05 | — | — | EP | disclosed |