Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.41 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 3/20 | 0.39 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19859857 | 0.86 | ADORA3 (0.46) | ADORA3ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL15833215 | 0.85 | ADORA3 (0.52) | ADORA3ADORA2ASTING1 | |
| SCHEMBL15833022 | 0.85 | ADORA3 (0.52) | ADORA3ADORA2ASTING1 | |
| SCHEMBL15837259 | 0.83 | ADORA3 (0.39) | ADORA3ADORA2ASTING1 | |
| SCHEMBL19859805 | 0.82 | ADORA2A (0.62) | ADORA3MAPK1ADORA2A | |
| SCHEMBL17467675 | 0.81 | TAS1R3 (0.39) | ADORA3ADORA2A | |
| SCHEMBL31228204 | 0.79 | ADORA2A (0.50) | ADORA3LMNAADORA2A | |
| SCHEMBL12149438 | 0.78 | ADORA2A (0.66) | ADORA3ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL13559257 | 0.78 | ADORA2A (0.66) | ADORA3ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL13559231 | 0.78 | ADORA2A (0.66) | ADORA3ALDH1A1LMNAALBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190169221-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | Janssen Biopharma, Inc. | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190169221-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | PNP, NUDT1, NT5C3B | ADORA3 90/4885ALDH1A1 2186/4885LMNA 982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.