Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 16/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 16/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21078574 | 0.90 | ADK (0.34) | PRMT5WDR77ADK | |
| SCHEMBL19859761 | 0.86 | ADORA1 (0.39) | — | |
| SCHEMBL31228407 | 0.82 | ADK (0.36) | PRMT5WDR77ADK | |
| SCHEMBL19859727 | 0.79 | ADORA1 (0.39) | — | |
| SCHEMBL19859341 | 0.78 | PRMT5 (0.46) | PRMT5WDR77ADK | |
| SCHEMBL19859757 | 0.78 | PRMT5 (0.46) | PRMT5WDR77ADK | |
| SCHEMBL19859339 | 0.77 | PRMT5 (0.35) | PRMT5WDR77ADK | |
| SCHEMBL21078572 | 0.76 | ADORA3 (0.37) | — | |
| SCHEMBL23635185 | 0.75 | ADORA3 (0.42) | — | |
| SCHEMBL21046369 | 0.74 | TYMP (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190169221-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | Janssen Biopharma, Inc. | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190169221-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | PNP, NUDT1, NT5C3B | PRMT5 2886/4885WDR77 2822/4885NPSR1 1369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.