Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL9631051 | 0.90 | TAS2R38 (0.38) | ALDH1A1TSHRMITF | |
| SCHEMBL9353535 | 0.83 | TRPA1 (0.31) | ALDH1A1 | |
| Bromide SCHEMBL10656257 | 0.82 | HRH4 (0.31) | — | |
| Hydrochloric Acid SCHEMBL10655702 | 0.82 | — | — | |
| SCHEMBL461758 | 0.71 | — | — | |
| SCHEMBL175816 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL10653382 | 0.71 | — | — | |
| SCHEMBL11060370 | 0.70 | — | — | |
| Bromide SCHEMBL1263032 | 0.69 | — | — | |
| Iodide SCHEMBL11806511 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0357192-B1 | PROCESS FOR PREPARING SUBSTITUTED GUANYLTHIOUREAS | PFIZER INC. (US) | 1992-05-06 | — | — | EP | claimed |
| US-8158806-B2 | DAT1 | DEPARTMENT OF BIOTECHNOLOGY (IN) | 2012-04-17 | — | — | US | disclosed |
| US-20090298177-A1 | DAT1 | DEPARTMENT OF BIOTECHNOLOGY (IN) | 2009-12-03 | — | — | US | disclosed |
| US-20090018341-A1 | DAT1 | DEPARTMENT OF BIOTECHNOLOGY (IN) | 2009-01-15 | — | — | US | disclosed |
| US-20080132709-A1 | Dat1 | DEPARTMENT OF BIOTECHNOLOGY (IN) | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298177-A1 | DAT1 | TUBB1, TUBB6, TUBB | ALDH1A1 151/4885TSHR 2198/4885MITF 3124/4885 |
| US-20090018341-A1 | DAT1 | TUBB1, TUBB6, TUBB | ALDH1A1 151/4885TSHR 2198/4885MITF 3124/4885 |
| US-20080132709-A1 | Dat1 | TUBB1, TUBB6, TUBB | ALDH1A1 151/4885TSHR 2198/4885MITF 3124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.