Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | AGXT | P21549 | 2/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5651640 | 0.76 | MAOB (0.49) | MAOBMAPTLMNAPOLBSTAT3 | |
| SCHEMBL15669834 | 0.75 | FFAR1 (0.41) | MAOBMAPTLMNAPOLBSTAT3 | |
| Hydrochloric Acid SCHEMBL15669833 | 0.74 | MAOB (0.53) | MAOBMAPTLMNAPOLBSTAT3 | |
| SCHEMBL15350256 | 0.72 | KDM5A (0.54) | MAOBKDM5AKDM4CKDM5B | |
| SCHEMBL15351339 | 0.72 | LMNA (0.39) | MAOBMAPTLMNAPOLBSTAT3 | |
| SCHEMBL15351722 | 0.72 | MAOB (0.56) | MAOBMAOAALDH1A1MEN1KMT2A | |
| SCHEMBL15351653 | 0.69 | KDM5A (0.41) | MAOBLMNAHTTMAOAKMT2A | |
| SCHEMBL21078962 | 0.69 | KDM5A (0.41) | MAOBMAPTLMNAPOLBSTAT3 | |
| SCHEMBL20708295 | 0.68 | CHRNB2 (0.36) | — | |
| SCHEMBL31623890 | 0.68 | MAOA (0.51) | MAOBMAPTLMNASTAT3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841421-B1 | AMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC (JP) | 2019-06-05 | — | — | EP | disclosed |