SCHEMBL21082127

SCHEMBL21082127

CCOC(O)CCNC(=O)N[C@H](C=O)CSC/C=C(\C)CC/C=C(\C)CCC=C(C)C

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.48
ALDH1A1 P00352 1/20 0.48
MEN1 O00255 1/20 0.42
TRPA1 O75762 1/20 0.42
KMT2A Q03164 1/20 0.42
ICMT O60725 13/20 0.41
FNTA P49354 2/20 0.39
FNTB P49356 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21697739 0.89 MAPT (0.62) MAPTALDH1A1MEN1TRPA1KMT2A
SCHEMBL20218756 0.84 MAPT (0.50) MAPTALDH1A1MEN1TRPA1KMT2A
SCHEMBL21697758 0.77 MAPT (0.60) MAPTALDH1A1MEN1TRPA1KMT2A
SCHEMBL21697713 0.74 MAPT (0.57) MAPTALDH1A1MEN1TRPA1KMT2A
SCHEMBL21082128 0.74 MAPT (0.57) MAPTALDH1A1MEN1TRPA1KMT2A
SCHEMBL8012020 0.74 MAPT (0.54) MAPTALDH1A1MEN1TRPA1KMT2A
SCHEMBL20843594 0.73 MAPT (0.53) MAPTALDH1A1MEN1TRPA1KMT2A
SCHEMBL2456586 0.73 MAPT (0.64) MAPTALDH1A1MEN1TRPA1KMT2A
SCHEMBL20218789 0.73 MAPT (0.64) MAPTALDH1A1MEN1TRPA1KMT2A
SCHEMBL2456570 0.73 MAPT (0.64) MAPTALDH1A1MEN1TRPA1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10314802-B2 Isoprenyl compounds and methods thereof SIGNUM BIOSCIENCES, INC. (US) 2019-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10314802-B2 Isoprenyl compounds and methods thereof ALOX15B, ALOX15, ALOX5 MAPT 4014/4885ALDH1A1 882/4885MEN1 3337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.