SCHEMBL21082207

SCHEMBL21082207

CC(C)=CCC/C(C)=C/CC/C=C/CSC[C@H](NC(=O)/C=C/C(=O)O)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.63
MAPT P10636 1/20 0.63
ICMT O60725 9/20 0.52
FNTA P49354 8/20 0.51
FNTB P49356 8/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2817130 0.91 MAPT (0.76) ALDH1A1MAPTICMTFNTAFNTB
SCHEMBL15395811 0.91 MAPT (0.76) ALDH1A1MAPTICMTFNTAFNTB
SCHEMBL1816232 0.91 MAPT (0.76) ALDH1A1MAPTICMTFNTAFNTB
SCHEMBL2817126 0.91 MAPT (0.76) ALDH1A1MAPTICMTFNTAFNTB
SCHEMBL14328070 0.91 MAPT (0.76) ALDH1A1MAPTICMTFNTAFNTB
SCHEMBL21697861 0.84 MAPT (0.65) ALDH1A1MAPTICMTFNTAFNTB
SCHEMBL13135746 0.84 MAPT (0.76) ALDH1A1MAPTICMTFNTAFNTB
SCHEMBL13175182 0.82 MAPT (0.72) ALDH1A1MAPTICMTFNTAFNTB
SCHEMBL21697860 0.82 ALDH1A1 (0.58) ALDH1A1MAPTICMTFNTAFNTB
SCHEMBL13252990 0.81 MAPT (0.71) ALDH1A1MAPTICMTFNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10314802-B2 Isoprenyl compounds and methods thereof SIGNUM BIOSCIENCES, INC. (US) 2019-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10314802-B2 Isoprenyl compounds and methods thereof ALOX15B, ALOX15, ALOX5 ALDH1A1 882/4885MAPT 4014/4885ICMT 267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.