SCHEMBL2108348

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2109174	0.78	RAB9A (0.45)	ECE1CYP2A6CHEK2LOXL2ALDH1A1
	SCHEMBL13731115	0.78	P4HTM (0.64)	P4HTMP4HA1MIFKDM4EALDH1A1
	SCHEMBL2177044	0.77	PDPK1 (0.60)	PDPK1CHEK2LOXL2KDM4EALDH1A1
	SCHEMBL27673803	0.76	PDPK1 (0.58)	PDPK1CHEK2LOXL2KDM4EALDH1A1
	SCHEMBL10722440	0.75	EGLN1 (0.56)	CYP2A6CHEK2P4HTMP4HA1MIF
	SCHEMBL722198	0.73	PDPK1 (0.77)	PDPK1CYP2A6CHEK2LOXL2ALDH1A1
	SCHEMBL13680491	0.73	ALDH1A1 (0.55)	ECE1CYP2A6P4HTMP4HA1MIF
	SCHEMBL3722096	0.73	TRPM4 (0.47)	PDPK1CHEK2LOXL2PTGDR2ABL1
	SCHEMBL2816868	0.72	CHEK2 (0.55)	PDPK1CHEK2LOXL2PTGDR2HDAC2
	SCHEMBL23832336	0.72	CYP2A6 (0.55)	PDPK1CYP2A6CHEK2LOXL2ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.