Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 8/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.32 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2106707 | 0.86 | NAAA (0.49) | MIFNAAATRPA1ALDH1A1CYP3A4 | |
| SCHEMBL30529263 | 0.75 | MIF (0.45) | MIFNAAATRPA1ALDH1A1CYP3A4 | |
| SCHEMBL3933178 | 0.73 | MIF (0.52) | MIFNAAATRPA1ALDH1A1CYP3A4 | |
| SCHEMBL2022735 | 0.71 | MIF (0.52) | MIFTRPA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL2108224 | 0.71 | MIF (0.56) | MIFTRPA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL2106339 | 0.71 | MIF (0.43) | MIFTRPA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL29374969 | 0.71 | MIF (0.52) | MIFTRPA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL138081 | 0.70 | DPP4 (0.41) | ALDH1A1DPP4PYCR1BRD4BRD2 | |
| SCHEMBL29137937 | 0.70 | DPP4 (0.41) | ALDH1A1DPP4PYCR1BRD4BRD2 | |
| SCHEMBL4780073 | 0.69 | MIF (0.63) | MIFTRPA1ALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020021544-A1 | CANNABIDIOL AND METHYLTHIO-BUTYL-ISOTHIOCYANATE FOR TREATING INFLAMMATORY DISEASES | BOL PHARMA LTD. (IL) | 2020-01-30 | — | — | WO | disclosed |
| US-20120208879-A1 | METHODS AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR TREATING PSORIASIS | GAVISH-GALILEE BIO APPLICATIONS LTD. (IL) | 2012-08-16 | — | — | US | disclosed |
| US-8158161-B2 | Methods and pharmaceutical compositions useful for treating psoriasis | S.U.L.V.E. LTD. (IL) | 2012-04-17 | — | — | US | disclosed |
| US-20080044497-A1 | Methods and Pharmaceutical Compositions Useful for Treating Psoriasis | S.U.L.V.E. LTD. (IL) | 2008-02-21 | — | — | US | disclosed |
| EP-1841320-A2 | METHODS AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR TREATING PSORIASIS | S.U.L.V.E. Ltd. (IL) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006075330-A2 | METHODS AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR TREATING PSORIASIS | S.U.L.V.E. LTD. (IL) | 2006-07-20 | — | — | WO | disclosed |