SCHEMBL30529263

SCHEMBL30529263

Fc1cc(F)c(CN=C=S)cc1F

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MIF P14174 7/20 0.45
TRPA1 O75762 2/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
HPGD P15428 1/20 0.39
DPP4 P27487 4/20 0.34
NAAA Q02083 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1649587 0.78 DPP4 (0.34) DPP4
SCHEMBL2106707 0.75 NAAA (0.49) MIFTRPA1ALDH1A1CYP3A4HPGD
SCHEMBL2106339 0.75 MIF (0.43) MIFTRPA1ALDH1A1CYP3A4HPGD
SCHEMBL2108378 0.75 MIF (0.43) MIFTRPA1ALDH1A1CYP3A4HPGD
SCHEMBL3933178 0.72 MIF (0.52) MIFTRPA1ALDH1A1CYP3A4HPGD
SCHEMBL5573138 0.69 MIF (0.49) MIFTRPA1ALDH1A1CYP3A4HPGD
SCHEMBL28839005 0.69 MIF (0.58) MIF
SCHEMBL29374969 0.67 MIF (0.52) MIFTRPA1ALDH1A1CYP3A4HPGD
SCHEMBL2022735 0.67 MIF (0.52) MIFTRPA1ALDH1A1CYP3A4HPGD
SCHEMBL2023050 0.67 MIF (0.52) MIFTRPA1ALDH1A1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023165459-A1 COMPOUNDS AS SARS-COV-2 INHIBITORS FOCHON BIOSCIENCES , LTD. (CN) 2023-09-07 WO disclosed