Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | MIF | P14174 | 5/20 | 0.43 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | TRAP1 | Q12931 | 5/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2108378 | 0.86 | MIF (0.43) | NAAAMIFPYCR1TRPA1ALDH1A1 | |
| SCHEMBL7750833 | 0.82 | PYCR1 (0.46) | NAAAPYCR1AKR1B1KDM1ATRAP1 | |
| SCHEMBL2106339 | 0.79 | MIF (0.43) | MIFTRPA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL30529263 | 0.75 | MIF (0.45) | NAAAMIFTRPA1ALDH1A1CYP3A4 | |
| SCHEMBL3933178 | 0.73 | MIF (0.52) | NAAAMIFTRPA1ALDH1A1CYP3A4 | |
| SCHEMBL28839005 | 0.72 | MIF (0.58) | MIF | |
| SCHEMBL29374969 | 0.71 | MIF (0.52) | MIFTRPA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL2022735 | 0.71 | MIF (0.52) | MIFTRPA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL28689565 | 0.71 | PYCR1 (0.40) | NAAAPYCR1AKR1B1KDM1ATRAP1 | |
| SCHEMBL27686599 | 0.71 | NAAA (0.48) | NAAAPYCR1AKR1B1KDM1APDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020021544-A1 | CANNABIDIOL AND METHYLTHIO-BUTYL-ISOTHIOCYANATE FOR TREATING INFLAMMATORY DISEASES | BOL PHARMA LTD. (IL) | 2020-01-30 | — | — | WO | disclosed |
| US-20120208879-A1 | METHODS AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR TREATING PSORIASIS | GAVISH-GALILEE BIO APPLICATIONS LTD. (IL) | 2012-08-16 | — | — | US | disclosed |
| US-8158161-B2 | Methods and pharmaceutical compositions useful for treating psoriasis | S.U.L.V.E. LTD. (IL) | 2012-04-17 | — | — | US | disclosed |
| US-20080044497-A1 | Methods and Pharmaceutical Compositions Useful for Treating Psoriasis | S.U.L.V.E. LTD. (IL) | 2008-02-21 | — | — | US | disclosed |
| EP-1841320-A2 | METHODS AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR TREATING PSORIASIS | S.U.L.V.E. Ltd. (IL) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006075330-A2 | METHODS AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR TREATING PSORIASIS | S.U.L.V.E. LTD. (IL) | 2006-07-20 | — | — | WO | disclosed |