SCHEMBL2108453

SCHEMBL2108453

COC=C(C(=O)OOc1cccc(Oc2ccccc2F)c1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GCK P35557 2/20 0.41
LPAR1 Q92633 5/20 0.40
LPAR5 Q9H1C0 5/20 0.40
PARP10 Q53GL7 1/20 0.40
PPARG P37231 1/20 0.39
ALDH1A1 P00352 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
MRGPRX4 Q96LA9 1/20 0.36
KDM4E B2RXH2 2/20 0.36
POLB P06746 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
GAA P10253 1/20 0.36
AKR1C3 P42330 1/20 0.35
PGR P06401 1/20 0.35
CXCL8 P10145 1/20 0.34
PYGM P11217 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2108447 1.00 GCK (0.41) GCKLPAR1LPAR5PARP10PPARG
SCHEMBL2107655 0.81 MEN1 (0.51) ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL2107651 0.81 MEN1 (0.51) ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL2107178 0.81 KDM4E (0.38) GCKPARP10PPARGMEN1KMT2A
SCHEMBL2107181 0.81 KDM4E (0.38) GCKPARP10PPARGMEN1KMT2A
SCHEMBL29359347 0.80 ALDH1A1 (0.42) ALDH1A1MEN1KMT2AKDM4ERAB9A
SCHEMBL30051737 0.79 KDM4E (0.44) GCKLPAR1LPAR5PARP10PPARG
SCHEMBL2858455 0.79 KDM4E (0.44) GCKLPAR1LPAR5PARP10PPARG
SCHEMBL2858451 0.79 KDM4E (0.44) GCKLPAR1LPAR5PARP10PPARG
SCHEMBL8338930 0.79 P4HB (0.42) ALDH1A1MEN1KMT2AGAAAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9314030-B2 Particulate wood preservative and method for producing same KOPPERS PERFORMANCE CHEMICALS INC. (US) 2016-04-19 US disclosed
US-20150056258-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME OSMOSE, INC. (US) 2015-02-26 US disclosed
US-8722198-B2 Method of preserving wood by injecting particulate wood preservative slurry OSMOSE, INC. (US) 2014-05-13 US disclosed
US-20130164362-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME OSMOSE, INC. (US) 2013-06-27 US disclosed
US-8158208-B2 Method of preserving wood by injecting particulate wood preservative slurry OSMOSE, INC. (US) 2012-04-17 US disclosed
US-20090223408-A1 Use of Sub-Micron Copper Salt Particles in Wood Preservation PHIBROWOOD, LLC (US) 2009-09-10 US disclosed
US-20090123505-A1 Particulate Wood Preservative and Method for Producing Same PHIBROWOOD, LLC (US) 2009-05-14 US disclosed
EP-1830989-A2 USE OF SUB-MICRON COPPER SALT PARTICLES IN WOOD PRESERVATION Phibro-Tech, Inc. (US) 2007-09-12 EP disclosed
WO-2006065684-A2 USE OF SUB-MICRON COPPER SALT PARTICLES IN WOOD PRESERVATION PHIBRO-TECH, INC. (US) 2006-06-22 WO disclosed
WO-2006042128-A2 TREATMENT OF WOOD WITH AN INJECTABLE WOOD PRESERVATIVE SLURRY HAVING BIOCIDAL PARTICLES PHIBRO-TECH, INC. (US) 2006-04-20 WO disclosed
US-20060062926-A1 Use of sub-micron copper salt particles in wood preservation KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC) 2006-03-23 US disclosed
US-20050252408-A1 Particulate wood preservative and method for producing same KOPPERS PERFORMANCE CHEMICALS NEW ZEALAND LIMITED (F/K/A OSMOSE NEW ZEALAND) (NZ) 2005-11-17 US disclosed
US-5925675-A N-sulfonyliminodithio compounds useful for in plant and material protection BAYER AKTIENGESELLSCHAFT (DE) 1999-07-20 US disclosed
US-5874025-A Timber preservative containing a copper compound BAYER AKTIENGESELLSCHAFT (DE) 1999-02-23 US disclosed
US-5672617-A Medicaments containing 1-thiocarbamoyl-5-hydroxy-pyrazoles and their use as agents for combating septic shock BAYER AKTIENGESELLSCHAFT (DE) 1997-09-30 US disclosed