SCHEMBL21085332

SCHEMBL21085332

CC(C)(C)c1cccc2ccc(I)cc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.39
CYP2A6 P11509 3/20 0.34
CYP1A2 P05177 2/20 0.34
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
TYMS P04818 2/20 0.34
PTPRC P08575 1/20 0.34
ALDH1A1 P00352 6/20 0.33
TSHR P16473 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
KIF11 P52732 1/20 0.33
HSD17B10 Q99714 3/20 0.32
HPGD P15428 1/20 0.32
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31
HIF1A Q16665 1/20 0.31
CYP1B1 Q16678 1/20 0.31
PLA2G1B P04054 1/20 0.30
MAPT P10636 1/20 0.30
ATG4B Q9Y4P1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23074859 0.78 CYP2A6 (0.59) CA2CYP2A6CYP1A2GABRA1GABRB2
SCHEMBL28423964 0.77 CA2 (0.46) CA2CYP2A6CYP1A2GABRA1GABRB2
SCHEMBL13433295 0.77 CYP2A6 (0.43) CA2CYP2A6CYP1A2GABRA1GABRB2
SCHEMBL26522361 0.77 CYP2A6 (0.43) CA2CYP2A6CYP1A2GABRA1GABRB2
SCHEMBL26522334 0.77 MCL1 (0.53) CA2CYP1A2GABRA1GABRB2ALDH1A1
SCHEMBL23922264 0.77 CA2 (0.39) CA2CYP2A6CYP1A2GABRA1GABRB2
SCHEMBL27117088 0.77 CYP1A2 (0.43) CA2CYP2A6CYP1A2GABRA1GABRB2
SCHEMBL4818310 0.74 KIF11 (0.48) CA2CYP2A6CYP1A2GABRA1GABRB2
SCHEMBL29972825 0.74 KIF11 (0.48) CA2CYP2A6CYP1A2GABRA1GABRB2
SCHEMBL252402 0.74 KIF11 (0.48) CA2CYP2A6CYP1A2GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4206210-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-07-05 EP disclosed
EP-3613751-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2020-02-26 EP disclosed
EP-3492528-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2019-06-05 EP disclosed