Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1920809 | 0.79 | KIF11 (0.56) | KIF11KEAP1NFE2L2CDK5CDK5R1 | |
| SCHEMBL17613793 | 0.67 | ACHE (0.47) | KIF11KEAP1NFE2L2CDK5CDK5R1 | |
| SCHEMBL21086234 | 0.65 | KIF11 (0.46) | KIF11KEAP1NFE2L2CDK5CDK5R1 | |
| SCHEMBL8365326 | 0.64 | KEAP1 (0.47) | KIF11KEAP1NFE2L2CDK2MAPT | |
| SCHEMBL1921035 | 0.64 | KIF11 (0.45) | KIF11KEAP1NFE2L2CDK5CDK5R1 | |
| SCHEMBL27118739 | 0.63 | CHUK (0.58) | KIF11KEAP1NFE2L2CDK5CDK5R1 | |
| SCHEMBL29445080 | 0.63 | CHUK (0.58) | KIF11KEAP1NFE2L2CDK5CDK5R1 | |
| SCHEMBL1337539 | 0.63 | KEAP1 (0.51) | KIF11KEAP1NFE2L2CHUKACHE | |
| SCHEMBL1920226 | 0.63 | KIF11 (0.47) | KIF11KEAP1NFE2L2CHUKACHE | |
| SCHEMBL17613784 | 0.62 | CDK5 (0.47) | KIF11KEAP1NFE2L2CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2694057-B1 | LIPOXYGENASE INHIBITORS | STANFORD RES INST INT (US) | 2019-06-05 | — | — | EP | disclosed |