Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 7/20 | 0.42 |
| ▸ | CNR1 | P21554 | 5/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7879429 | 0.85 | LMNA (0.47) | HTTHIF1ALMNAHSD17B10PLA2G4B | |
| SCHEMBL2108647 | 0.81 | SMN1; SMN2 (0.54) | HTTHIF1ALMNAHSD17B10AR | |
| SCHEMBL4071970 | 0.81 | LMNA (0.44) | HTTHIF1ALMNAHSD17B10PLA2G4B | |
| SCHEMBL13190989 | 0.81 | HTT (0.66) | HTTHIF1ALMNAHSD17B10AR | |
| SCHEMBL2108186 | 0.80 | CNR2 (0.49) | LMNAHSD17B10CNR2CNR1AR | |
| SCHEMBL9636030 | 0.79 | MAPK1 (0.55) | HTTHIF1ALMNAHSD17B10CNR2 | |
| SCHEMBL7167448 | 0.79 | HTT (0.43) | HTTHIF1ALMNAHSD17B10PLA2G4B | |
| SCHEMBL19677468 | 0.79 | HTT (0.59) | HTTHIF1ALMNAHSD17B10AR | |
| SCHEMBL22043203 | 0.76 | HTT (0.57) | HTTHIF1ALMNAHSD17B10AR | |
| SCHEMBL26461593 | 0.76 | HTT (0.57) | HTTHIF1ALMNAHSD17B10AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158088-B2 | Extractant compositions for co-extracting cesium and strontium, a method of separating cesium and strontium from an aqueous feed, and calixarene compounds | BATTELLE ENERGY ALLIANCE, LLC (US) | 2012-04-17 | — | — | US | claimed |