Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 12/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7167448 | 0.86 | HTT (0.43) | LMNAHSD17B10PLA2G4BHTTHIF1A | |
| SCHEMBL4071969 | 0.83 | SMN1; SMN2 (0.49) | LMNAHSD17B10HTTHIF1AAR | |
| SCHEMBL8364493 | 0.81 | S1PR1 (0.56) | LMNAHSD17B10PLA2G4BHIF1AKDM4E | |
| SCHEMBL2108648 | 0.81 | HTT (0.48) | LMNAHSD17B10PLA2G4BHTTHIF1A | |
| SCHEMBL7879429 | 0.79 | LMNA (0.47) | LMNAHSD17B10PLA2G4BHTTHIF1A | |
| SCHEMBL9636030 | 0.75 | MAPK1 (0.55) | LMNAHSD17B10HTTHIF1AAR | |
| SCHEMBL2108186 | 0.74 | CNR2 (0.49) | LMNAHSD17B10ARCNR2CNR1 | |
| SCHEMBL7165673 | 0.72 | HTT (0.44) | LMNAHSD17B10HTTHIF1AAR | |
| SCHEMBL10492948 | 0.72 | NR5A1 (0.53) | CNR2CNR1 | |
| SCHEMBL10513794 | 0.71 | NR5A1 (0.56) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174503-B1 | NUCLEAR WASTES TREATMENT, ESPECIALLY WASTES WITH A HIGH CONCENTRATION OF COMPETING ALKALI METAL CATIONS | LOCKHEED MARTIN ENERGY RESEARCH CORPORATION | 2001-01-16 | — | — | US | claimed |
| US-7524469-B2 | Extractant composition including crown ether and calixarene extractants | BATTELLE ENERGY ALLIANCE, LLC (US) | 2009-04-28 | — | — | US | disclosed |
| US-20080179568-A1 | EXTRACTANT COMPOSITION INCLUDING CROWN ETHER AND CALIXARENE EXTRACTANTS | ENERGY, UNITED STATES DEPARTMENT OF | 2008-07-31 | — | — | US | disclosed |
| US-7291316-B2 | Cesium and strontium extraction using a mixed extractant solvent including crown ether and calixarene extractants | BATTELLE ENERGY ALLIANCE, LLC (US) | 2007-11-06 | — | — | US | disclosed |
| US-20050211955-A1 | Cesium and strontium extraction using a mixed extractant solvent including crown ether and calixarene extractants | BATTELLE ENERGY ALLIANCE, LLC | 2005-09-29 | — | — | US | disclosed |
| US-6566561-B1 | Phenoxy fluoro-alcohols, their preparation, and their use as phase modifiers and solvating agents | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF ENERGY | 2003-05-20 | — | — | US | disclosed |
| US-6174503-B1 | NUCLEAR WASTES TREATMENT, ESPECIALLY WASTES WITH A HIGH CONCENTRATION OF COMPETING ALKALI METAL CATIONS | LOCKHEED MARTIN ENERGY RESEARCH CORPORATION | 2001-01-16 | — | — | US | disclosed |
| WO-1999012878-A1 | SOLVENT AND PROCESS FOR EXTRACTING CESIUM FROM ALKALINE WASTE SOLUTIONS | LOCKHEED MARTIN ENERGY RES COR (US) | 1999-03-18 | — | — | WO | disclosed |