Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636026 | 0.84 | ALDH1A1 (0.57) | MAPK1KDM4ETDP1ALDH1A1LMNA | |
| SCHEMBL9636165 | 0.83 | ALDH1A1 (0.62) | MAPK1KDM4ETDP1ALDH1A1LMNA | |
| SCHEMBL18120597 | 0.80 | KDM4E (0.71) | MAPK1KDM4ETDP1ALDH1A1LMNA | |
| SCHEMBL7879429 | 0.79 | LMNA (0.47) | LMNAHTTHIF1AHSD17B10CNR1 | |
| SCHEMBL10078135 | 0.79 | HTT (0.61) | MAPK1KDM4ETDP1ALDH1A1LMNA | |
| SCHEMBL2108648 | 0.79 | HTT (0.48) | MAPK1KDM4ETDP1LMNAGAA | |
| SCHEMBL502214 | 0.79 | MAPK1 (0.59) | MAPK1KDM4ETDP1ALDH1A1LMNA | |
| SCHEMBL1101535 | 0.79 | HTT (0.61) | MAPK1KDM4ETDP1ALDH1A1LMNA | |
| SCHEMBL2108186 | 0.77 | CNR2 (0.49) | LMNAHSD17B10ARCNR1CNR2 | |
| SCHEMBL4074135 | 0.76 | CYP3A4 (0.62) | MAPK1ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239536-B1 | LUBRICANT COMPOSITIONS | CIBA-GEIGY AG (CH) | 1992-06-24 | — | — | EP | claimed |
| EP-0239536-A2 | Lubricant compositions | CIBA-GEIGY AG (CH) | 1987-09-30 | — | — | EP | claimed |
| EP-0239536-B1 | LUBRICANT COMPOSITIONS | CIBA-GEIGY AG (CH) | 1992-06-24 | — | — | EP | disclosed |
| EP-0239536-A2 | Lubricant compositions | CIBA-GEIGY AG (CH) | 1987-09-30 | — | — | EP | disclosed |