Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18947601 | 0.80 | — | — | |
| SCHEMBL13674820 | 0.77 | — | — | |
| SCHEMBL12528297 | 0.77 | HTT (0.36) | ALDH1A1 | |
| SCHEMBL20704188 | 0.74 | CHRNB2 (0.32) | ALDH1A1 | |
| SCHEMBL12051933 | 0.74 | CCNA2 (0.36) | — | |
| SCHEMBL31229804 | 0.73 | CHRNB2 (0.31) | ALDH1A1 | |
| Nitrous Acid SCHEMBL28883343 | 0.70 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL16913805 | 0.69 | PIK3C3 (0.35) | — | |
| SCHEMBL20203264 | 0.69 | — | — | |
| SCHEMBL22695577 | 0.69 | ALDH1A1 (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10662189-B2 | PDE4 inhibitor | Shijiazhuang Sagacity New Drug Development Co., Ltd. (CN) | 2020-05-26 | — | — | US | disclosed |
| US-20190177318-A1 | PDE4 INHIBITOR | MEDSHINE DISCOVERY INC. (CN) | 2019-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190177318-A1 | PDE4 INHIBITOR | PDE4A, PDE12, PDE4B | ALDH1A1 363/4885 |
| US-10662189-B2 | PDE4 inhibitor | PDE4A, PDE12, PDE4B | ALDH1A1 363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.