Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 17/20 | 0.38 |
| ▸ | HTR6 | P50406 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12127658 | 0.88 | HTR6 (0.41) | PTGDR2HTR6 | |
| SCHEMBL21088821 | 0.82 | PTGDR2 (0.35) | PTGDR2 | |
| SCHEMBL12128235 | 0.81 | APP (0.37) | PTGDR2HTR6 | |
| SCHEMBL12128199 | 0.81 | APP (0.35) | PTGDR2HTR6 | |
| SCHEMBL12128227 | 0.79 | KEAP1 (0.36) | PTGDR2 | |
| SCHEMBL21088212 | 0.78 | HTR6 (0.34) | PTGDR2HTR6 | |
| SCHEMBL12127548 | 0.78 | PTGDR2 (0.35) | PTGDR2HTR6 | |
| SCHEMBL21088824 | 0.78 | PTGDR2 (0.35) | PTGDR2 | |
| SCHEMBL6710520 | 0.76 | HTR6 (0.52) | PTGDR2HTR6 | |
| SCHEMBL12127652 | 0.76 | HTR6 (0.40) | PTGDR2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558446-B1 | NOVEL COMPOUNDS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH AMYLOID OR AMYLOID-LIKE PROTEINS | AC IMMUNE SA (CH) | 2019-06-12 | — | — | EP | disclosed |