Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29301788 | 0.93 | PTGS2 (0.33) | PTGS2 | |
| SCHEMBL19819835 | 0.93 | PTGS2 (0.33) | PTGS2 | |
| SCHEMBL1120183 | 0.73 | HPGD (0.34) | — | |
| SCHEMBL18948717 | 0.71 | GPR84 (0.31) | — | |
| SCHEMBL18948839 | 0.70 | — | — | |
| SCHEMBL2870668 | 0.69 | HCAR2 (0.50) | PTGS2 | |
| SCHEMBL1529233 | 0.68 | ALOX15 (0.42) | — | |
| Lithium SCHEMBL31258223 | 0.68 | ALOX15 (0.42) | — | |
| SCHEMBL20927053 | 0.68 | — | — | |
| SCHEMBL13464275 | 0.68 | HPGD (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3495360-A1 | HETEROARYL SUBSTITUTED HETEROCYCLYL SULFONES | Grünenthal GmbH (DE) | 2019-06-12 | — | — | EP | disclosed |