Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | GCK | P35557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17173639 | 0.66 | RIPK1 (0.39) | RIPK1 | |
| SCHEMBL24974203 | 0.62 | KCNN4 (0.35) | — | |
| SCHEMBL13358887 | 0.60 | HRH4 (0.36) | RIPK1 | |
| SCHEMBL20757797 | 0.59 | — | — | |
| SCHEMBL23638523 | 0.58 | HSP90AA1 (0.38) | — | |
| SCHEMBL20621385 | 0.57 | LMNA (0.32) | — | |
| SCHEMBL23336008 | 0.57 | NLRP3 (0.32) | — | |
| SCHEMBL20886019 | 0.56 | RECQL (0.33) | — | |
| SCHEMBL26773438 | 0.56 | BRPF1 (0.32) | — | |
| SCHEMBL20757440 | 0.56 | CHRM2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3495360-A1 | HETEROARYL SUBSTITUTED HETEROCYCLYL SULFONES | Grünenthal GmbH (DE) | 2019-06-12 | — | — | EP | disclosed |