Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.37 |
| ▸ | FEN1 | P39748 | 3/20 | 0.37 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.36 |
| ▸ | WDR48 | Q8TAF3 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | EDNRB | P24530 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30287137 | 0.86 | USP1 (0.44) | USP1ALOX5APFEN1DCTPP1WDR48 | |
| SCHEMBL4481266 | 0.86 | USP1 (0.44) | USP1ALOX5APFEN1DCTPP1WDR48 | |
| SCHEMBL20150112 | 0.81 | TYK2 (0.39) | USP1ALOX5APFEN1WDR48ADRA1A | |
| SCHEMBL18367724 | 0.81 | KDM4E (0.43) | CYP1A2MAPK1EDNRA | |
| SCHEMBL6527857 | 0.81 | DCTPP1 (0.45) | CYP1A2ALOX5APFEN1DCTPP1ADRA1A | |
| SCHEMBL28129242 | 0.79 | DCTPP1 (0.41) | CYP1A2ALOX5APFEN1DCTPP1ADRA1A | |
| SCHEMBL18367721 | 0.77 | CYP2A6 (0.46) | USP1CYP1A2WDR48 | |
| SCHEMBL19980775 | 0.77 | DCTPP1 (0.48) | CYP1A2ALOX5APFEN1DCTPP1ADRA1A | |
| SCHEMBL17194971 | 0.75 | P2RX7 (0.41) | CYP1A2ALOX5APFEN1DCTPP1ADRA1A | |
| SCHEMBL21091001 | 0.75 | GABRA1 (0.39) | USP1CYP1A2ALOX5APFEN1WDR48 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3495358-A1 | AMIDE-SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHA RESPONSES | Bristol-Myers Squibb Company (US) | 2019-06-12 | — | — | EP | disclosed |