SCHEMBL21092385

SCHEMBL21092385

NCCCCCCOCCCCc1ccccc1S(N)(=O)=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 2/20 0.50
ADRB1 P08588 2/20 0.50
ADRB3 P13945 2/20 0.50
MGLL Q99685 1/20 0.38
CA1 P00915 5/20 0.37
CA2 P00918 5/20 0.37
CA12 O43570 3/20 0.37
CA9 Q16790 3/20 0.37
SSTR2 P30874 1/20 0.37
SSTR4 P31391 1/20 0.37
CA4 P22748 2/20 0.37
CA6 P23280 2/20 0.37
CYP2C9 P11712 2/20 0.37
MAOA P21397 1/20 0.37
CA5A P35218 1/20 0.37
CA7 P43166 1/20 0.37
CA14 Q9ULX7 1/20 0.37
CA5B Q9Y2D0 1/20 0.37
SCN1A P35498 2/20 0.37
SCN2A Q99250 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6671590 0.91 CA1 (0.44) ADRB2ADRB1ADRB3MGLLCA1
SCHEMBL10553004 0.85 ADRB2 (0.46) ADRB2ADRB1ADRB3MGLLCA1
SCHEMBL10550048 0.85 ADRB2 (0.46) ADRB2ADRB1ADRB3MGLLCA1
SCHEMBL28043042 0.85 CA2 (0.45) ADRB2ADRB1ADRB3MGLLCA1
SCHEMBL8355995 0.85 CA2 (0.48) ADRB2ADRB1ADRB3MGLLCA1
SCHEMBL7114697 0.84 ADRB2 (0.47) ADRB2ADRB1ADRB3MGLLCA1
SCHEMBL1876554 0.80 KCNA3 (0.50) ADRB2ADRB1ADRB3CA1CA2
SCHEMBL731097 0.78 TAAR1 (0.52) CA1CA2CA12CA9CA4
SCHEMBL579137 0.78 LIPG (0.50) MGLLCA2
SCHEMBL16713743 0.78 CYP3A4 (0.43) ADRB2ADRB1ADRB3MGLLCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019112913-A1 BETA-2 SELECTIVE ADRENERGIC RECEPTOR AGONISTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2019-06-13 WO disclosed