Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.42 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.42 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187587 | 1.00 | ALDH1A1 (0.55) | ALDH1A1TDP1MAPK1TSHRHSD17B10 | |
| SCHEMBL2109241 | 1.00 | ALDH1A1 (0.55) | ALDH1A1TDP1MAPK1TSHRHSD17B10 | |
| SCHEMBL8619130 | 0.87 | LMNA (0.55) | ALDH1A1TDP1MAPK1TSHRHSD17B10 | |
| Isothiocyanate SCHEMBL9197203 | 0.87 | TDP1 (0.44) | ALDH1A1TDP1MAPK1TSHRHSD17B10 | |
| SCHEMBL9753362 | 0.87 | LMNA (0.55) | ALDH1A1TDP1MAPK1TSHRHSD17B10 | |
| SCHEMBL2474219 | 0.86 | LMNA (0.61) | ALDH1A1TDP1MAPK1TSHRHSD17B10 | |
| SCHEMBL2474220 | 0.86 | LMNA (0.61) | ALDH1A1TDP1MAPK1TSHRHSD17B10 | |
| SCHEMBL2472953 | 0.82 | MAPT (0.46) | ALDH1A1TDP1MAPK1TSHRHSD17B10 | |
| SCHEMBL2472954 | 0.82 | MAPT (0.46) | ALDH1A1TDP1MAPK1TSHRHSD17B10 | |
| Azobenzene SCHEMBL1405620 | 0.80 | ALDH1A1 (0.75) | ALDH1A1TDP1MAPK1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012130850-A1 | TISSUE TARGETING BY MEANS OF ONCOCIDAL BRIDGED DIPHENYL DERIVATIVES FOR THE SELECTIVE TREATMENT OF SEXUAL ORGAN TUMORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-10-04 | — | — | WO | disclosed |
| US-8158685-B2 | Method for bone growth | STEINER GREGORY GENE (US) | 2012-04-17 | — | — | US | disclosed |
| WO-2007011575-A2 | METHOD AND COMPOSITION FOR BONE GROWTH | STEINER GREGORY (US) | 2007-01-25 | — | — | WO | disclosed |
| US-20060008502-A1 | Method and composition for bone growth | STEINER GREGORY G | 2006-01-12 | — | — | US | disclosed |
| US-20030170318-A1 | Fluoride compositions and uses thereof | STEINER HEALTHCARE LLC | 2003-09-11 | — | — | US | disclosed |
| US-20020041902-A1 | Fluoride as a chemoprotective and chemotheraputic agent for cancer in mammals | STEINER GREGORY GENE (US) | 2002-04-11 | — | — | US | disclosed |
| WO-2002028401-A1 | FLUORIDE AS A CHEMOPROTECTIVE AND CHEMOTHERAPEUTIC AGENT FOR CANCER IN MAMMALS | STEINER GREGORY (US) | 2002-04-11 | — | — | WO | disclosed |