Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.39 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.39 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753362 | 1.00 | LMNA (0.55) | LMNAALDH1A1MAPK1HSD17B10TDP1 | |
| SCHEMBL187587 | 0.87 | ALDH1A1 (0.55) | LMNAALDH1A1MAPK1HSD17B10TDP1 | |
| SCHEMBL2109239 | 0.87 | ALDH1A1 (0.55) | LMNAALDH1A1MAPK1HSD17B10TDP1 | |
| SCHEMBL2109241 | 0.87 | ALDH1A1 (0.55) | LMNAALDH1A1MAPK1HSD17B10TDP1 | |
| Azobenzene SCHEMBL9551792 | 0.80 | ALDH1A1 (0.67) | LMNAALDH1A1MAPK1HSD17B10TDP1 | |
| Dimethyl Yellow SCHEMBL7720567 | 0.77 | ALDH1A1 (0.78) | ALDH1A1MAPK1HSD17B10TDP1TSHR | |
| Methyl Yellow SCHEMBL7720573 | 0.77 | ALDH1A1 (0.78) | ALDH1A1MAPK1HSD17B10TDP1TSHR | |
| Isothiocyanate SCHEMBL9197203 | 0.76 | TDP1 (0.44) | LMNAALDH1A1MAPK1HSD17B10TDP1 | |
| SCHEMBL2474219 | 0.75 | LMNA (0.61) | LMNAALDH1A1MAPK1HSD17B10TDP1 | |
| SCHEMBL2474220 | 0.75 | LMNA (0.61) | LMNAALDH1A1MAPK1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361284-B1 | T cell growth factor | LUDWIG INST CANCER RES (US) | 1998-06-17 | — | — | EP | disclosed |
| US-5750377-A | SYNERGISTIC WITH INTERLEUKINS | LUDWIG INSTITUTE FOR CANCER RESEARCH (US) | 1998-05-12 | — | — | US | disclosed |
| US-5587302-A | ISOLATED POLYNUCLEOTIDES ENCODES POLYPEPTIDE INTERLEUKINS | LUDWIG INSTITUTE FOR CANCER RESEARCH (US) | 1996-12-24 | — | — | US | disclosed |
| EP-0466854-A4 | T CELL GROWTH FACTOR | — | 1993-03-31 | — | — | EP | disclosed |
| US-5157112-A | Supports interleukin-2 and interleukin-4 independent growth of helper T cells | LUDWIG INSTITUTE FOR CANCER RESEARCH (CH) | 1992-10-20 | — | — | US | disclosed |
| EP-0466854-A1 | T CELL GROWTH FACTOR | LUDWIG INSTITUTE FOR CANCER RESEARCH (US) | 1992-01-22 | — | — | EP | disclosed |
| WO-1991010738-A1 | T CELL GROWTH FACTOR | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-07-25 | — | — | WO | disclosed |
| EP-0361284-A2 | T cell growth factor | LUDWIG INSTITUTE FOR CANCER RESEARCH (US) | 1990-04-04 | — | — | EP | disclosed |
| US-4828979-A | BIOTINYLATED | LIFE TECHNOLOGIES, INC. (US) | 1989-05-09 | — | — | US | disclosed |