Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540758 | 0.76 | CYP1A2 (0.43) | CYP1A2CYP19A1MAPTKMT2ALMNA | |
| SCHEMBL7155162 | 0.76 | CCR2 (0.51) | CYP19A1MAPTKMT2AMEN1HPGD | |
| SCHEMBL27447038 | 0.75 | CYP1A2 (0.46) | CYP1A2CYP19A1MAPTKMT2ALMNA | |
| SCHEMBL9542139 | 0.74 | DHFR (0.50) | MAPTKMT2ALMNAMEN1DHFR | |
| SCHEMBL21093059 | 0.73 | MAPT (0.57) | CYP1A2CYP19A1MAPTKMT2ALMNA | |
| SCHEMBL19135849 | 0.72 | DHFR (0.43) | CYP1A2KMT2ADHFRSLC2A1 | |
| SCHEMBL19335128 | 0.71 | CYP19A1 (0.53) | CYP1A2CYP19A1MAPTKMT2ALMNA | |
| SCHEMBL6232857 | 0.71 | CYP19A1 (0.56) | CYP1A2CYP19A1MAPTKMT2ALMNA | |
| SCHEMBL6230356 | 0.71 | CYP19A1 (0.59) | CYP1A2CYP19A1MAPTKMT2ALMNA | |
| SCHEMBL9486251 | 0.70 | CYP19A1 (0.52) | CYP1A2CYP19A1MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993010119-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-05-27 | — | — | WO | disclosed |
| EP-0542497-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |