Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 6/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | VEGFA | P15692 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21093657 | 0.88 | CA1 (0.43) | SLC6A3CNR2SLC6A2TRPM8CA1 | |
| SCHEMBL21094089 | 0.86 | CNR2 (0.38) | SLC6A3CNR2TRPM8CA1CA2 | |
| SCHEMBL21094101 | 0.85 | KIF11 (0.41) | SLC6A3CNR2TRPM8CA1CA2 | |
| SCHEMBL21094102 | 0.85 | KIF11 (0.38) | SLC6A3CNR2TRPM8CA1CA2 | |
| SCHEMBL21094103 | 0.83 | CTPS1 (0.41) | CNR2CA1CA2 | |
| SCHEMBL21094093 | 0.79 | MAPT (0.39) | TRPM8MAPTLMNAKMT2AKIF11 | |
| SCHEMBL21094410 | 0.75 | NPC1 (0.40) | CNR2TRPM8CA1CA2MAPT | |
| SCHEMBL21094394 | 0.74 | NPC1 (0.41) | TRPM8CA1CA2MAPT | |
| SCHEMBL21094092 | 0.74 | GABRA5 (0.40) | — | |
| SCHEMBL21094397 | 0.73 | NPC1 (0.39) | TRPM8CA1CA2JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019112024-A1 | PYRROLIDINE COMPOUND | キッセイ薬品工業株式会社 | 2019-06-13 | — | — | WO | disclosed |