Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 7/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21093661 | 0.88 | SLC6A3 (0.39) | CA1CA2CNR2SLC6A3SLC6A2 | |
| SCHEMBL21094101 | 0.87 | KIF11 (0.41) | CA1CA2CNR2SLC6A3KIF11 | |
| SCHEMBL21094102 | 0.87 | KIF11 (0.38) | CA1CA2CNR2SLC6A3KIF11 | |
| SCHEMBL21094089 | 0.86 | CNR2 (0.38) | CA1CA2CNR2SLC6A3KIF11 | |
| SCHEMBL21094103 | 0.86 | CTPS1 (0.41) | CA1CA2CNR2 | |
| SCHEMBL21094093 | 0.79 | MAPT (0.39) | KIF11TRPM8 | |
| SCHEMBL21094410 | 0.78 | NPC1 (0.40) | CA1CA2CNR2TRPM8VCP | |
| SCHEMBL21094394 | 0.77 | NPC1 (0.41) | CA1CA2TRPM8NPC1RAB9A | |
| SCHEMBL21094092 | 0.76 | GABRA5 (0.40) | NPC1RAB9A | |
| SCHEMBL21094393 | 0.74 | NPC1 (0.40) | CA1CA2TRPM8VCPNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019112024-A1 | PYRROLIDINE COMPOUND | キッセイ薬品工業株式会社 | 2019-06-13 | — | — | WO | disclosed |