Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.36 |
| ▸ | MCTS1 | Q9ULC4 | 2/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21094395 | 0.90 | ALDH1A1 (0.38) | SMN1; SMN2 | |
| SCHEMBL21094405 | 0.88 | PKM (0.40) | MAPTLMNATRPM8SLC16A3MCTS1 | |
| SCHEMBL21093972 | 0.88 | CHRM3 (0.35) | MAPTLMNAKMT2AGPBAR1 | |
| SCHEMBL21094101 | 0.84 | KIF11 (0.41) | MAPTORAI1KIF11TRPM8BRD4 | |
| SCHEMBL21094102 | 0.82 | KIF11 (0.38) | MAPTORAI1KIF11TRPM8BRD4 | |
| SCHEMBL21094089 | 0.81 | CNR2 (0.38) | MAPTKIF11TRPM8BRD4 | |
| SCHEMBL21093657 | 0.79 | CA1 (0.43) | KIF11TRPM8 | |
| SCHEMBL21093964 | 0.79 | PTGES (0.38) | GPBAR1PTGES | |
| SCHEMBL21093661 | 0.79 | SLC6A3 (0.39) | MAPTLMNAKMT2AKIF11TRPM8 | |
| SCHEMBL21093670 | 0.77 | TRPM8 (0.43) | MAPTLMNAKMT2ATRPM8L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019112024-A1 | PYRROLIDINE COMPOUND | キッセイ薬品工業株式会社 | 2019-06-13 | — | — | WO | disclosed |