Dietifen

Dietifen

SCHEMBL2109562

CCN(CC)CCOc1ccc(C(=O)CCc2ccccc2)cc1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.62
RAB9A P51151 1/20 0.62
CYP2D6 P10635 2/20 0.60
HTT P42858 2/20 0.60
CYP1A2 P05177 1/20 0.60
LTA4H P09960 1/20 0.60
CYP2C9 P11712 1/20 0.60
CYP2C19 P33261 1/20 0.60
BCHE P06276 5/20 0.58
ACHE P22303 5/20 0.58
ESR1 P03372 4/20 0.56
EBP Q15125 3/20 0.56
SIGMAR1 Q99720 3/20 0.56
EGFR P00533 3/20 0.56
KCNH2 Q12809 2/20 0.56
CHRM2 P08172 2/20 0.56
ADRA2A P08913 2/20 0.56
ADORA3 P0DMS8 2/20 0.56
CHRM1 P11229 2/20 0.56
PTGS1 P23219 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9360139 0.91 BCHE (0.65) NPC1RAB9ABCHEACHEABCB1
SCHEMBL10680278 0.87 CYP2D6 (0.63) CYP2D6HTTCYP1A2LTA4HCYP2C9
SCHEMBL864569 0.84 EBP (0.63) CYP2D6HTTBCHEACHEESR1
SCHEMBL11531601 0.82 THRA (0.48) NPC1RAB9ACYP2D6HTTCYP1A2
SCHEMBL4008981 0.81 LTA4H (0.56) NPC1RAB9ACYP2D6HTTCYP1A2
Hydrochloric Acid SCHEMBL11528511 0.81 THRA (0.47) NPC1RAB9ACYP2D6HTTCYP1A2
SCHEMBL9360115 0.81 EGFR (0.63) NPC1RAB9ABCHEACHEEGFR
SCHEMBL5810064 0.81 EBP (0.68) CYP2D6HTTCYP1A2LTA4HCYP2C9
SCHEMBL8008499 0.81 NPC1 (0.68) NPC1RAB9AEGFRKMT2AMEN1
SCHEMBL10885211 0.81 EBP (0.71) NPC1RAB9ACYP2D6HTTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3840378-B1 VIDEO DECODING METHOD AND VIDEO DECODER HUAWEI TECH CO LTD (CN) 2025-07-30 EP claimed
EP-3540783-B1 RADIATION-TOLERANT UNIT MOSFET HARDENED AGAINST SINGLE EVENT EFFECT AND TOTAL IONIZING DOSE EFFECT KOREA ADVANCED INST SCI & TECH (KR) 2024-11-20 EP claimed
EP-2966462-B1 Vertical hall device SENIS AG (CH) 2022-04-20 EP claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
CN-118728675-A Main device of inclined surface roller way mini pyramid perpetual downward perpetual circulation acting force machine 陈明 2024-10-01 CN disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-11191719-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2021-12-07 US disclosed
US-10463611-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2019-11-05 US disclosed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US disclosed
US-6680047-B2 FOR USE IN ULTRASOUND IMAGING, CONTRAST AGENTS AMERSHAM HEALTH AS (NO) 2004-01-20 US disclosed
US-20020102215-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 US disclosed
US-20020102217-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 US disclosed
US-6331289-B1 ULTRASOUND CONTRAST AGENTS, SUSPENSION IN AQUEOUS CARRIER LIQUID OF A REPORTER COMPRISING GAS-CONTAINING OR GAS-GENERATING MATERIAL, AGENT CAPABLE OF FORMING AT LEAST TWO TYPES OF BINDING PAIRS WITH TARGET; REPORTER BEING CONJUGATED NYCOMED IMAGING AS (NO) 2001-12-18 US disclosed
US-6264917-B1 MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT NYCOMED IMAGING AS (NO) 2001-07-24 US disclosed
US-6261537-B1 TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES NYCOMED IMAGING AS (NO) 2001-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020102215-A1 Diagnostic/therapeutic agents BID, FUS, FABP1 NPC1 533/4885RAB9A 1715/4885CYP2D6 4855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.