Ditophal

Ditophal

SCHEMBL2109565

CCSC(=O)c1cccc(C(=O)SCC)c1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 2/20 0.46
NOS1 P29475 2/20 0.46
NOS2 P35228 2/20 0.46
HDAC8 Q9BY41 8/20 0.44
HDAC6 Q9UBN7 8/20 0.44
HDAC3 O15379 7/20 0.44
HDAC4 P56524 7/20 0.44
HDAC1 Q13547 7/20 0.44
HDAC7 Q8WUI4 7/20 0.44
HDAC2 Q92769 7/20 0.44
HDAC10 Q969S8 7/20 0.44
HDAC11 Q96DB2 7/20 0.44
HDAC9 Q9UKV0 7/20 0.44
HDAC5 Q9UQL6 7/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
KMT2A Q03164 3/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
TDP1 Q9NUW8 2/20 0.41
ATM Q13315 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL778106 0.88 HPGD (0.54) HDAC8HDAC6SMN1; SMN2KMT2AALDH1A1
SCHEMBL14114091 0.87 ALDH1A1 (0.54) NOS3NOS1NOS2HDAC8HDAC6
SCHEMBL1641518 0.84 HDAC3 (0.55) NOS3NOS1NOS2HDAC8HDAC6
SCHEMBL7527942 0.84 HDAC3 (0.63) NOS3NOS1NOS2HDAC8HDAC6
SCHEMBL69963 0.83 SMN1; SMN2 (0.44) NOS3NOS1NOS2SMN1; SMN2KMT2A
SCHEMBL24703568 0.81 HDAC3 (0.44) NOS3NOS1NOS2HDAC8HDAC6
SCHEMBL24703569 0.81 PTPN1 (0.44) NOS1HDAC8HDAC6HDAC3HDAC4
SCHEMBL1479121 0.80 KMT2A (0.40) NOS3NOS1NOS2HDAC8HDAC6
SCHEMBL5830962 0.80 CYP3A4 (0.43) NOS3NOS1NOS2HDAC8HDAC6
SCHEMBL27501402 0.76 ALDH1A1 (0.49) NOS3NOS1NOS2KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119044866-A Revising method of atmospheric electric field monitoring result 无锡学院 2024-11-29 CN claimed
US-11648382-B2 Microneedle structure and manufacturing method and manufacturing apparatus for the same KOREA INSTITUTE OF MACHINERY & MATERIALS (KR) 2023-05-16 US claimed
CN-114613011-A Human body 3D (three-dimensional) bone behavior identification method based on graph attention convolutional neural network 东华大学 2022-06-10 CN claimed
CN-114239370-A Method for calculating critical space ion flow field of large wind turbine generator in thunderstorm process 华北电力大学 2022-03-25 CN claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20260139275-A1 STEM CELL BASED DELIVERY OF TUMOR-SPECIFIC RETROVIRAL VECTORS THE REGENTS OF THE UNIV OF CALIFORNIA (US) 2026-05-21 US disclosed
EP-3987386-B1 ADAPTIVE HOVER OPERATION OF TOUCH INSTRUMENTS MICROSOFT TECHNOLOGY LICENSING LLC (US) 2026-03-25 EP disclosed
US-20260073128-A1 System and Method for Generating and Publishing Electronic Content from Predetermined Templates 1206881 ALBERTA LTD. (CA) 2026-03-12 US disclosed
US-12528065-B2 Nanocapsules and process of making and using same The Government of the United States, as represented by the Director of the Defense Health Agency (US) 2026-01-20 US disclosed
US-12443789-B2 System and method for generating and publishing electronic content from predetermined templates 1206881 ALBERTA LTD. (CA) 2025-10-14 US disclosed
US-20020102215-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 US disclosed
US-20020102217-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 US disclosed
US-6331289-B1 ULTRASOUND CONTRAST AGENTS, SUSPENSION IN AQUEOUS CARRIER LIQUID OF A REPORTER COMPRISING GAS-CONTAINING OR GAS-GENERATING MATERIAL, AGENT CAPABLE OF FORMING AT LEAST TWO TYPES OF BINDING PAIRS WITH TARGET; REPORTER BEING CONJUGATED NYCOMED IMAGING AS (NO) 2001-12-18 US disclosed
US-6264917-B1 MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT NYCOMED IMAGING AS (NO) 2001-07-24 US disclosed
US-6261537-B1 TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES NYCOMED IMAGING AS (NO) 2001-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260073128-A1 System and Method for Generating and Publishing Electronic Content from Predetermined Templates CFL1, EMD, TEC NOS3 3036/4885NOS1 2783/4885NOS2 2721/4885
US-20260139275-A1 STEM CELL BASED DELIVERY OF TUMOR-SPECIFIC RETROVIRAL VECTORS MYC, MYCBP, FUS NOS3 4658/4885NOS1 4595/4885NOS2 4546/4885
US-12528065-B2 Nanocapsules and process of making and using same PTEN, PHOSPHO1, CAD NOS3 83/4885NOS1 581/4885NOS2 215/4885
US-20020102215-A1 Diagnostic/therapeutic agents BID, FUS, FABP1 NOS3 4103/4885NOS1 4058/4885NOS2 4290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.