Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4943059 | 0.98 | SLC6A3 (0.45) | SLC6A3SMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL854723 | 0.84 | SMN1; SMN2 (0.45) | SLC6A3SMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL2819185 | 0.81 | SLC6A3 (0.47) | SLC6A3KMT2ARAB9ANPC1POLB | |
| SCHEMBL10163704 | 0.79 | SLC6A3 (0.46) | SLC6A3KMT2ANPC1DRD2HTR2A | |
| SCHEMBL7226659 | 0.79 | SLC6A3 (0.50) | SLC6A3SMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL16603147 | 0.79 | SLC6A3 (0.46) | SLC6A3KMT2ANPC1DRD2HTR2A | |
| SCHEMBL348008 | 0.79 | SLC6A3 (0.46) | SLC6A3KMT2ANPC1DRD2HTR2A | |
| SCHEMBL129911 | 0.79 | SLC6A3 (0.46) | SLC6A3KMT2ANPC1DRD2HTR2A | |
| SCHEMBL2439238 | 0.79 | SLC6A3 (0.46) | SLC6A3KMT2ANPC1DRD2HTR2A | |
| SCHEMBL7180800 | 0.79 | SLC6A3 (0.46) | SLC6A3KMT2ANPC1DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115417829-A | Preparation method of ritonavir enantiomer | 武汉海特生物创新医药研究有限公司 | 2022-12-02 | — | — | CN | claimed |
| CN-109054648-A | Serosity combination for chemically mechanical polishing | LTCAM有限公司 | 2018-12-21 | — | — | CN | claimed |
| CN-104419326-A | Slurry composition for chemical mechanical polishing | COWON INNOTECH INC | 2015-03-18 | — | — | CN | claimed |
| EP-0657442-A2 | Thiazole derivate and process for its preparation | ASAHI CHEMICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | claimed |
| JP-7157477-A | — | — | None | — | — | JP | disclosed |
| CN-109485617-B | Preparation method of N-methyl-2-isopropyl-4-thiazole methylamine | 贵州永诺菲特生物制药有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-115417829-A | Preparation method of ritonavir enantiomer | 武汉海特生物创新医药研究有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-115417829-A | Preparation method of ritonavir enantiomer | 武汉海特生物创新医药研究有限公司 | 2022-12-02 | — | — | CN | disclosed |
| US-10968203-B2 | Pyrimidinyl-pyridyloxy-naphthyl compounds and methods of treating IRE1-related diseases and disorders | GENENTECH, INC. (US) | 2021-04-06 | — | — | US | disclosed |
| US-20210093618-A1 | SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2021-04-01 | — | — | US | disclosed |
| EP-3696171-A1 | MODULATORS OF PHARMACOKINETIC PROPERTIES OF THERAPEUTICS | Gilead Sciences, Inc. (US) | 2020-08-19 | — | — | EP | disclosed |
| EP-3018125-B1 | NOVEL COMPOUND, ORGANIC CATION TRANSPORTER 3 DETECTION AGENT, AND ORGANIC CATION TRANSPORTER 3 ACTIVITY INHIBITOR | SHIN NIPPON BIOMEDICAL LABORATORIES LTD (JP) | 2020-08-05 | — | — | EP | disclosed |
| JP-H07157477-A | PRODUCTION OF THIAZOLE DERIVATIVE | ASAHI KAGAKU KOGYO KK | 1995-06-20 | — | — | JP | disclosed |
| EP-0657442-A2 | Thiazole derivate and process for its preparation | ASAHI CHEMICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | disclosed |
| EP-0657442-A2 | Thiazole derivate and process for its preparation | ASAHI CHEMICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | disclosed |
| WO-1995007696-A1 | PHARMACEUTICAL COMPOSITION OF HIV-PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1995-03-23 | — | — | WO | disclosed |
| WO-1994014436-A1 | RETROVIRAL PROTEASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1994-07-07 | — | — | WO | disclosed |
| EP-0032058-B1 | THIAZOLE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-10-26 | — | — | EP | disclosed |
| US-4411900-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-10-25 | — | — | US | disclosed |
| EP-0032058-A1 | Thiazole derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10968203-B2 | Pyrimidinyl-pyridyloxy-naphthyl compounds and methods of treating IRE1-related diseases and disorders | XBP1, ERN1, ATF4 | SLC6A3 4116/4885SMN1; SMN2 379/4885KMT2A 4455/4885 |
| US-20210093618-A1 | SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | BRIX1, RDX, SULT2A1 | SLC6A3 1320/4885SMN1; SMN2 2483/4885KMT2A 277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.