Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | GRK2 | P25098 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9812568 | 0.96 | PPARG (0.47) | CNR2KMT2AMEN1PPARGRAB9A | |
| SCHEMBL8438245 | 0.79 | ALDH1A1 (0.57) | CNR2KMT2AMEN1PPARGRAB9A | |
| SCHEMBL11150910 | 0.75 | MAPT (0.65) | CNR2KMT2AMEN1MAPK1POLB | |
| SCHEMBL5184899 | 0.71 | LMNA (0.57) | KMT2AMEN1PPARGRAB9ARXFP1 | |
| SCHEMBL13650238 | 0.71 | MAPT (0.54) | CNR2KMT2AMEN1PKMMAPK1 | |
| SCHEMBL11863483 | 0.69 | CNR2 (0.51) | CNR2KMT2AMEN1PPARGRAB9A | |
| SCHEMBL8930956 | 0.68 | ALDH1A1 (0.72) | CNR2KMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL238296 | 0.68 | CNR2 (0.45) | CNR2KMT2AMEN1PKMMAPK1 | |
| SCHEMBL23876926 | 0.67 | ALDH1A1 (0.61) | KMT2AMEN1RAB9APOLBALDH1A1 | |
| SCHEMBL11863379 | 0.67 | ALDH1A1 (0.51) | CNR2KMT2AMEN1PPARGRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158375-B2 | Polymer and method of measuring cholesterol therewith | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2012-04-17 | — | — | US | disclosed |
| EP-2239281-A2 | Novel polymer and method for determining cholesterol using the same | Wako Pure Chemical Industries, Ltd. (JP) | 2010-10-13 | — | — | EP | disclosed |
| EP-0964249-B1 | Method for measuring LDL-cholesterol | WAKO PURE CHEM IND LTD (JP) | 2004-11-10 | — | — | EP | disclosed |
| EP-0878716-B1 | Measurement of LDL-cholesterol | WAKO PURE CHEM IND LTD (JP) | 2003-06-04 | — | — | EP | disclosed |
| EP-0964249-A2 | Method for measuring LDL-cholesterol | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1999-12-15 | — | — | EP | disclosed |
| US-5925534-A | MEASURING AMOUNT OF CHOLESTEROL IN LOW DENSITY LIPOPROTEINS BY MIXING SAMPLE WITH REAGENT IN PRESENCE OF POLYANION AND AMPHOTERIC SURFACTANT, OPTICALLY MEASURING REACTION PRODUCT | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-20 | — | — | US | disclosed |
| US-5879901-A | REAGENT COMPRISING CHOLESTEROL ESTERASE AND CHOLESTEROL OXIDASE, AT LEAST ONE OF WHICH IS MODIFIED BY BEING BOUND TO SUGAR COMPOUND; FOR DIRECT MEASUREMENT BY SPECTROPHOTOGRAPHIC ABSORBANCE | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0878716-A1 | Measurement of LDL-cholesterol | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1998-11-18 | — | — | EP | disclosed |
| US-5814472-A | REACTING LIVING SAMPLE WITH CHOLESTEROL OXIDASE OR CHOLESTEROL DEHYDROGENASE IN PRESENCE OF AMPHOTERIC SURFACTANT AND CYCLODEXTRIN | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0402094-B1 | Process for measuring body fluid components | WAKO PURE CHEM IND LTD (JP) | 1996-08-28 | — | — | EP | disclosed |
| US-5384248-A | Process for measuring an analyte with an oxidase and an oxidizable color reagent and surfactants | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1995-01-24 | — | — | US | disclosed |
| EP-0402094-A2 | Process for measuring body fluid components | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1990-12-12 | — | — | EP | disclosed |