Tameridone

Tameridone

SCHEMBL2109716

Cn1c(=O)c2c(ncn2CCN2CCC(c3c[nH]c4ccccc34)CC2)n(C)c1=O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ADRA1D P25100 5/20 0.51
APEX1 P27695 1/20 0.50
MAPK1 P28482 1/20 0.50
ATM Q13315 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CYP2D6 P10635 1/20 0.50
SLC6A4 P31645 1/20 0.49
HTR7 P34969 2/20 0.49
HTR2A P28223 1/20 0.49
HTR6 P50406 1/20 0.48
CHRM2 P08172 1/20 0.48
HTR1A P08908 1/20 0.48
CHRM1 P11229 1/20 0.48
DRD2 P14416 1/20 0.48
ADRA1A P35348 1/20 0.48
ADRA1B P35368 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tameridone SCHEMBL10869123 0.99 ADRA1D (0.52) ADRA1DAPEX1MAPK1ATMTDP1
Tameridone SCHEMBL10868163 0.96 HTR2A (0.50) ADRA1DAPEX1MAPK1ATMTDP1
Tameridone SCHEMBL10866191 0.95 APEX1 (0.50) ADRA1DAPEX1MAPK1ATMTDP1
Fumaric Acid SCHEMBL10877875 0.89 ADRA1D (0.64) ADRA1DAPEX1MAPK1ATMTDP1
Fumaric Acid SCHEMBL10870276 0.89 ADRA1D (0.66) ADRA1DAPEX1MAPK1ATMTDP1
SCHEMBL10999018 0.88 HTR1A (0.54) ADRA1DSLC6A4HTR7HTR2AHTR6
SCHEMBL10871865 0.88 CYP1A2 (0.53) ADRA1DAPEX1MAPK1ATMTDP1
SCHEMBL10867871 0.88 OPRM1 (0.50) ADRA1DMAPK1ATMTDP1SLC6A4
SCHEMBL10872464 0.87 HTR7 (0.45) ADRA1DHTR7HTR6CHRM2HTR1A
SCHEMBL10866694 0.86 SLC6A4 (0.57) SLC6A4HTR7HTR2AHTR6HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
EP-0177087-A2 1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones JANSSEN PHARMACEUTICA N.V. (BE) 1986-04-09 EP claimed
US-4548939-A 1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones JANSSEN PHARMACEUTICA N. V. (BE) 1985-10-22 US claimed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-11191719-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2021-12-07 US disclosed
US-10463611-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2019-11-05 US disclosed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US disclosed
US-20140154313-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2014-06-05 US disclosed
EP-2717860-A1 CONTROLLED ABSORPTION WATER-SOLUBLE PHARMACEUTICALLY ACTIVE ORGANIC COMPOUND FORMULATION FOR ONCE-DAILY ADMINISTRATION STI Pharma, LLC (US) 2014-04-16 EP disclosed
US-20020102215-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 US disclosed
US-20020102217-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 US disclosed
US-6331289-B1 ULTRASOUND CONTRAST AGENTS, SUSPENSION IN AQUEOUS CARRIER LIQUID OF A REPORTER COMPRISING GAS-CONTAINING OR GAS-GENERATING MATERIAL, AGENT CAPABLE OF FORMING AT LEAST TWO TYPES OF BINDING PAIRS WITH TARGET; REPORTER BEING CONJUGATED NYCOMED IMAGING AS (NO) 2001-12-18 US disclosed
US-6264917-B1 MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT NYCOMED IMAGING AS (NO) 2001-07-24 US disclosed
US-6261537-B1 TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES NYCOMED IMAGING AS (NO) 2001-07-17 US disclosed
EP-0177087-A2 1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones JANSSEN PHARMACEUTICA N.V. (BE) 1986-04-09 EP disclosed
US-4548939-A 1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones JANSSEN PHARMACEUTICA N. V. (BE) 1985-10-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020102215-A1 Diagnostic/therapeutic agents BID, FUS, FABP1 ADRA1D 3096/4885APEX1 396/4885MAPK1 4783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.