Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28918152 | 1.00 | NTRK1 (0.43) | NTRK1PIK3C3 | |
| SCHEMBL28173612 | 0.88 | PIK3C3 (0.48) | NTRK1PIK3C3 | |
| SCHEMBL26968000 | 0.88 | PIK3C3 (0.48) | NTRK1PIK3C3 | |
| SCHEMBL27095477 | 0.88 | PIK3C3 (0.48) | NTRK1PIK3C3 | |
| SCHEMBL988331 | 0.79 | NTRK1 (0.48) | NTRK1 | |
| SCHEMBL983254 | 0.79 | NTRK1 (0.48) | NTRK1 | |
| SCHEMBL30151461 | 0.78 | NTRK1 (0.41) | NTRK1PIK3C3 | |
| SCHEMBL3769485 | 0.78 | NTRK1 (0.49) | NTRK1PIK3C3 | |
| SCHEMBL1082380 | 0.77 | NTRK1 (0.47) | NTRK1 | |
| SCHEMBL979031 | 0.76 | NTRK1 (0.49) | NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10344031-B2 | Substituted pyrazolo[1,5-a] pyridine as tropomyosin receptor kinase (Trk) inhibitors | DR. REDDY'S LABORATORIES LTD. (IN) | 2019-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10344031-B2 | Substituted pyrazolo[1,5-a] pyridine as tropomyosin receptor kinase (Trk) inhibitors | MUSK, DMPK, PNCK | NTRK1 4/4885PIK3C3 483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.