Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 5/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL317299 | 0.82 | RAPGEF4 (0.50) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL15929637 | 0.80 | RAPGEF4 (0.39) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL22064618 | 0.74 | RAPGEF4 (0.39) | RAPGEF4PSMD14COPS5ALDH1A1KDM4E | |
| SCHEMBL1402361 | 0.74 | RAPGEF4 (0.39) | RAPGEF4PSMD14COPS5ALDH1A1KDM4E | |
| SCHEMBL28859756 | 0.74 | ALDH1A1 (0.58) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL19972049 | 0.72 | KDM4E (0.46) | RAPGEF4PSMD14COPS5ALDH1A1KDM4E | |
| SCHEMBL7899006 | 0.71 | CRHR1 (0.36) | RAPGEF4PSMD14COPS5ALDH1A1KDM4E | |
| SCHEMBL11362981 | 0.71 | RAPGEF4 (0.41) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL11369300 | 0.71 | RAPGEF4 (0.41) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL11496778 | 0.70 | CYP3A4 (0.46) | RAPGEF4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11072742-B2 | Liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2021-07-27 | — | — | US | disclosed |
| US-20190185754-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2019-06-20 | — | — | US | disclosed |