Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 5/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17805473 | 0.84 | PSMD14 (0.38) | RAPGEF4PSMD14COPS5ALDH1A1TSHR | |
| SCHEMBL1183272 | 0.84 | RAPGEF4 (0.45) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL19326856 | 0.77 | — | — | |
| SCHEMBL1402361 | 0.77 | RAPGEF4 (0.39) | RAPGEF4PSMD14COPS5ALDH1A1KDM4E | |
| SCHEMBL21098030 | 0.74 | RAPGEF4 (0.38) | RAPGEF4PSMD14COPS5ALDH1A1KDM4E | |
| SCHEMBL19972049 | 0.74 | KDM4E (0.46) | RAPGEF4PSMD14COPS5ALDH1A1KDM4E | |
| SCHEMBL24198866 | 0.72 | ALDH1A1 (0.52) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL11496778 | 0.72 | CYP3A4 (0.46) | RAPGEF4ALDH1A1MAPT | |
| SCHEMBL24407647 | 0.72 | RAPGEF4 (0.36) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL9197813 | 0.72 | SELL (0.50) | RAPGEF4ALDH1A1KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3260917-B1 | PHOTOSENSITIVE RESIN COMPOSITION, PLANOGRAPHIC PRINTING ORIGINAL PLATE, METHOD FOR PRODUCING PLANOGRAPHIC PRINTING PLATE, AND POLYMER COMPOUND | FUJIFILM CORP (JP) | 2020-06-10 | — | — | EP | disclosed |