Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.49 |
| ▸ | RORC | P51449 | 3/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 2/20 | 0.38 |
| ▸ | SKP1 | P63208 | 2/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21063688 | 0.88 | GPR119 (0.51) | GPR119RORCNR1H2MEN1MAPT | |
| Lithium Ion SCHEMBL21063419 | 0.88 | GPR119 (0.39) | GPR119RORCNR1H2CKS1BSKP1 | |
| SCHEMBL23949975 | 0.84 | POLB (0.42) | RORCNR1H2CKS1BSKP1SKP2 | |
| SCHEMBL30257554 | 0.84 | POLB (0.42) | RORCNR1H2CKS1BSKP1SKP2 | |
| SCHEMBL30901868 | 0.84 | RORC (0.42) | GPR119RORCNR1H2CKS1BSKP1 | |
| SCHEMBL21063462 | 0.84 | RORC (0.42) | GPR119RORCNR1H2CKS1BSKP1 | |
| SCHEMBL28548511 | 0.82 | GPR119 (0.49) | GPR119RORCNR1H2CKS1BSKP1 | |
| SCHEMBL29977161 | 0.82 | GPR119 (0.49) | GPR119RORCNR1H2CKS1BSKP1 | |
| SCHEMBL569804 | 0.79 | RORC (0.40) | RORCNR1H2SMN1; SMN2SCD5POLB | |
| SCHEMBL1309072 | 0.78 | RORC (0.51) | GPR119RORCTSHRMAPK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019118612-A1 | TARGETING COMPOUNDS | ZAFGEN, INC. (US) | 2019-06-20 | — | — | WO | disclosed |