Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23949975 | 1.00 | POLB (0.42) | POLBNR1H2DRD2MEN1KMT2A | |
| SCHEMBL2264830 | 0.88 | DRD2 (0.47) | POLBDRD2MEN1KMT2ARAB9A | |
| SCHEMBL30257202 | 0.86 | POLB (0.41) | POLBNR1H2MEN1KMT2ARAB9A | |
| SCHEMBL23949979 | 0.86 | POLB (0.41) | POLBNR1H2MEN1KMT2ARAB9A | |
| SCHEMBL30901868 | 0.85 | RORC (0.42) | POLBNR1H2RORCHTTATM | |
| SCHEMBL21063462 | 0.85 | RORC (0.42) | POLBNR1H2RORCHTTATM | |
| SCHEMBL21098207 | 0.84 | GPR119 (0.49) | POLBNR1H2MEN1KMT2ARORC | |
| SCHEMBL28548511 | 0.84 | GPR119 (0.49) | POLBNR1H2RORCHTTATM | |
| SCHEMBL29977161 | 0.84 | GPR119 (0.49) | POLBNR1H2RORCHTTATM | |
| SCHEMBL16533508 | 0.83 | POLB (0.41) | POLBNR1H2DRD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4137481-A1 | ARYL OR HETEROARYL DERIVATIVE | Teijin Pharma Limited (JP) | 2023-02-22 | — | — | EP | disclosed |