Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 11/20 | 0.52 |
| ▸ | IGF1R | P08069 | 7/20 | 0.47 |
| ▸ | INSR | P06213 | 6/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.44 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21099489 | 0.92 | ALK (0.54) | ALKIGF1RINSRPTK2EGFR | |
| SCHEMBL21099658 | 0.86 | ALK (0.60) | ALKIGF1RINSRPTK2EGFR | |
| SCHEMBL19867338 | 0.85 | ALK (0.71) | ALKIGF1RINSRPTK2EGFR | |
| SCHEMBL21099502 | 0.85 | ALK (0.59) | ALKIGF1RINSRPTK2EGFR | |
| SCHEMBL21099605 | 0.84 | ALK (0.62) | ALKIGF1RINSRPTK2EGFR | |
| SCHEMBL21099556 | 0.84 | IRAK4 (0.56) | ALKPTK2EGFRMAP3K7 | |
| SCHEMBL21100183 | 0.83 | ALK (0.56) | ALKIGF1RINSRPTK2EGFR | |
| SCHEMBL19867178 | 0.83 | ALK (0.52) | ALKIGF1RINSRPTK2EGFR | |
| SCHEMBL21099428 | 0.83 | ALK (0.60) | ALKIGF1RINSRPTK2EGFR | |
| SCHEMBL21099499 | 0.83 | ALK (0.75) | ALKIGF1RINSREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3498716-A1 | THIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS | Hongyun Biotech Co., Ltd. (CN) | 2019-06-19 | — | — | EP | disclosed |