Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532280 | 0.79 | L3MBTL1 (0.46) | ALDH1A1NPC1RAB9AUSP2MAPT | |
| SCHEMBL18704620 | 0.79 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2NPC1RAB9AUSP2 | |
| SCHEMBL18595180 | 0.79 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2NPC1RAB9AUSP2 | |
| SCHEMBL18712308 | 0.76 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2NPC1RAB9AUSP2 | |
| SCHEMBL9674149 | 0.76 | LMNA (0.72) | ALDH1A1SMN1; SMN2RAB9AUSP2MAPT | |
| SCHEMBL19387563 | 0.76 | SIGMAR1 (0.46) | ALDH1A1SMN1; SMN2NPC1RAB9AUSP2 | |
| SCHEMBL14654212 | 0.76 | SMN1; SMN2 (0.58) | ALDH1A1SMN1; SMN2NPC1RAB9AUSP2 | |
| SCHEMBL25876044 | 0.75 | HRH3 (0.48) | ALDH1A1SMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL9530974 | 0.75 | BLM (0.50) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL24745066 | 0.74 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2NPC1RAB9AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10322191-B2 | Targeted conjugates and particles and formulations thereof | TARVEDA THERAPEUTICS, INC. (US) | 2019-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10322191-B2 | Targeted conjugates and particles and formulations thereof | SSTR5, SSTR1, SSTR4 | ALDH1A1 3199/4885SMN1; SMN2 966/4885NPC1 1288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.