Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.46 |
| ▸ | CDK6 | Q00534 | 8/20 | 0.45 |
| ▸ | CCND3 | P30281 | 7/20 | 0.45 |
| ▸ | CCNK | O75909 | 5/20 | 0.45 |
| ▸ | CDK9 | P50750 | 5/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 7/20 | 0.40 |
| ▸ | CCND1 | P24385 | 3/20 | 0.40 |
| ▸ | TTK | P33981 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CCND2 | P30279 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21099679 | 0.89 | CCND3 (0.51) | IRAK4CDK6CCND3CCNKCDK9 | |
| SCHEMBL21100193 | 0.89 | IRAK4 (0.59) | IRAK4ALKPLK1EGFR | |
| SCHEMBL21099605 | 0.85 | ALK (0.62) | ALKTTKEGFR | |
| SCHEMBL19867213 | 0.85 | ALK (0.62) | IRAK4CDK9ALKCDK4TTK | |
| SCHEMBL21100183 | 0.84 | ALK (0.56) | IRAK4ALKTTKPLK1EGFR | |
| SCHEMBL21099489 | 0.84 | ALK (0.54) | IRAK4ALKTTKPLK1EGFR | |
| SCHEMBL21099556 | 0.79 | IRAK4 (0.56) | IRAK4CDK6CCND3CCNKCDK9 | |
| SCHEMBL21099498 | 0.76 | ALK (0.60) | IRAK4ALKCDK4TTKPLK1 | |
| SCHEMBL21099658 | 0.76 | ALK (0.60) | IRAK4ALKCDK4TTKPLK1 | |
| SCHEMBL21099499 | 0.76 | ALK (0.75) | ALKPLK1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3498716-A1 | THIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS | Hongyun Biotech Co., Ltd. (CN) | 2019-06-19 | — | — | EP | disclosed |