Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21100614 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2HPGDP2RX7NPC1RAB9A | |
| SCHEMBL29411490 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2HPGDP2RX7NPC1RAB9A | |
| SCHEMBL21045225 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2HPGDP2RX7NPC1RAB9A | |
| SCHEMBL21100619 | 0.74 | SMN1; SMN2 (0.48) | SMN1; SMN2HPGDP2RX7NPC1RAB9A | |
| SCHEMBL6358755 | 0.74 | HTT (0.66) | SMN1; SMN2HPGDP2RX7TSHRALDH1A1 | |
| SCHEMBL2359602 | 0.72 | NAAA (0.61) | SMN1; SMN2HPGDP2RX7TSHRALDH1A1 | |
| SCHEMBL21100474 | 0.72 | P2RX7 (0.42) | SMN1; SMN2HPGDP2RX7NPC1RAB9A | |
| SCHEMBL29411607 | 0.72 | KDM4B (0.46) | SMN1; SMN2HPGDP2RX7NPC1RAB9A | |
| SCHEMBL21045402 | 0.72 | KDM4B (0.46) | SMN1; SMN2HPGDP2RX7NPC1RAB9A | |
| SCHEMBL21045126 | 0.71 | FLT3 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113242-A1 | TUBULIN INHIBITORS | Lin BioScience, LLC (US) | 2019-06-13 | — | — | WO | disclosed |