Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 12/20 | 0.46 |
| ▸ | RXRG | P48443 | 10/20 | 0.46 |
| ▸ | RXRB | P28702 | 11/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594667 | 0.89 | RXRA (0.54) | RXRARXRGRXRBNAAAKIF11 | |
| SCHEMBL17625196 | 0.84 | MMP3 (0.43) | RXRARXRB | |
| SCHEMBL24211077 | 0.82 | RXRA (0.50) | RXRARXRGRXRBKIF11NOTUM | |
| SCHEMBL24211025 | 0.82 | RXRA (0.50) | RXRARXRGRXRBKIF11NOTUM | |
| SCHEMBL18051412 | 0.80 | IDO1 (0.36) | NOTUMIDH1 | |
| SCHEMBL2267261 | 0.80 | KIF11 (0.57) | RXRARXRGRXRBNAAAKIF11 | |
| SCHEMBL24518592 | 0.80 | RXRA (0.48) | RXRARXRGRXRBKIF11NOTUM | |
| SCHEMBL13802327 | 0.80 | KIF11 (0.62) | RXRARXRGRXRBARKIF11 | |
| SCHEMBL13170619 | 0.78 | RXRA (0.47) | RXRARXRGRXRBARKIF11 | |
| SCHEMBL26375411 | 0.78 | KIF11 (0.53) | RXRARXRGRXRBKIF11NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10329486-B2 | Cyanostilbenes | ROLIC AG (CH) | 2019-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329486-B2 | Cyanostilbenes | LATS1, LATS2, CRY1 | RXRA 1412/4885RXRG 1754/4885RXRB 771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.